更新时间:2011-01-18 16:38:35
【中图分类号】:r644【文献标识码】:a
【文章编号】:1004-597x(2007)12-0001-04
【摘要】目的:探索一种理想的眼烧伤治疗方法。方法:动物实验和临床研究相结合。将36只酸、碱眼化学烧伤的新西兰白兔随机分为实验组和对照组,实验组应用羊膜移植治疗,对照组按常规治疗。将55例(88只)眼烧伤患者随机分为治疗组和对照组,治疗组应用羊膜移植治疗,对照组按常规治疗。结果:动物实验显示实验组眼感染率及角膜溃疡、穿孔率远低于对照组(p<0.05)。临床研究显示治疗组治愈率远高于对照组,两组比较差异有显著性意义(p<0.05)。结论:羊膜移植对眼烧伤具有良好的治疗效果。
【关键词】烧伤;眼;羊膜;治疗
researchontreatmentofocularburnsbyamnioticmembranetransplantation
dengxian
(departmentofburn,beihaipeople'shospital,beihai536000,guangxi,china)
【abstract】objectives:toinvestigateanidealtherapeuticmethodforocularburns.methods:36casesofnewzealandwhiterabbitswitheyesofacidburnoralkaliburnwererandomlydividedintoexperimentgroupandcontrolgroup.theeyesinexperimentgroupweretreatedbyamnioticmembranetransplantation.thoseincontrolgroupwereperformedasusual.55cases(88eyes)ofpatientswithocularburnswererandomlydividedintotreatmentgroupandcontrolgroup.theeyesintreatmentgroupweretreatedbyamnioticmembranetransplantation.othersincontrolgroupwereperformedasusual.results:theexperimentalstudyshowedthattherateofocularinfection,corneaulcerandperforationinexperimentgroupwereobviouslylowerthanthoseincontrolgroup(p2so4或2%~5%naoh溶液1~2滴滴入兔眼结膜囊内造成眼前段ii~iii度烧伤,眼烧伤分度按国际通用roper-hall标准分度将眼烧伤分为4度:i度:无角膜水肿混浊及角膜缘缺血;ii度:角膜水肿混浊,但可窥见虹膜纹理,角膜缘缺血范围1/2全周,近角膜缘部结膜缺血坏死。